What is EBOO?

What is EBOO?

Middle age man getting EBOO Therapy procedure

The Complete Guide to the “Dialysis” for Your Immune System

If you are searching for the most advanced method to detoxify your body, reduce chronic inflammation, and reset your immune system, you have likely found EBOO (Extracorporeal Blood Oxygenation and Ozonation).

While traditional ozone therapies have been used for decades, EBOO represents a quantum leap in technology. It is not just a “boost”; it is a systemic overhaul.


The “Plain English” Definition

What is it?

EBOO therapy—short for Extracorporeal Blood Oxygenation and Ozonation—is an advanced form of ozone therapy that combines medical ozone with blood filtration and oxygenation. It is considered one of the most efficient and comprehensive oxidative therapies available today, primarily used to detoxify the blood, boost immune function, and improve circulation.

In other words, it is an advanced medical procedure that involves a closed-loop blood filtration system. Think of it as a modern, high-tech dialysis for your immune system.

How is it different?

Most ozone treatments are static—they treat a small, fixed amount of blood. EBOO is dynamic. It pulls blood from one arm, runs it through a specialized medical device that filters, ozonates, and oxygenates it, and returns it to your other arm in a continuous flow.

This process allows us to treat a massive volume of blood, up to 2 to 3 liters, in a single 45-minute session.

The Visual Difference:

  • Old School Ozone (MAH): Imagine injecting a small amount of gas into a syringe of blood. It is effective for immune modulation, but it is limited by volume (treating only about 5-10% of your total blood).
  • New School EBOO: Imagine a car wash for your circulatory system. It treats a much larger volume of blood (approximately 2 liters), physically filtering out debris while supercharging your cells with oxygen.

The Science: Mechanisms of Action

It isn’t magic; it is advanced fluid dynamics and biochemistry. EBOO operates on a three-pronged mechanism to scrub your blood systemically.

1. Filtration (The Physical Barrier)

This is the “killer feature” that separates EBOO from every other ozone therapy. The device uses a hollow-fiber filter, similar to a dialysis cartridge. As your blood flows through these microscopic fibers, the filter physically traps:

  • Heavy Fats & Cholesterol: Reducing viscosity and improving circulation.
  • Cellular Debris: Dead cells and metabolic waste that clog your system.
  • Inflammatory Proteins: Including cytokines and viral remnants.
  • Heavy Metals: Often bound to proteins in the blood.

You can often see this captured “sludge” in the filter after the session—a visible testament to the toxic load removed from your body.

2. Ozonation (The Pathogen Killer)

Within the filter, Ozone gas (O3) is introduced to the blood. Because ozone is highly unstable, it reacts immediately. This creates a momentary “oxidative shock”—a calculated stressor that:

  • Destroys Pathogens: Bacteria, viruses, fungi, and parasites are anaerobic (they hate oxygen). Ozone disrupts their cell envelopes, killing them on contact.
  • Modulates the Immune System: It triggers the release of signaling molecules (cytokines) that tell your immune system to wake up and hunt down infections.

3. Oxygenation (The Energy Boost)

The process saturates your red blood cells with oxygen. We aren’t just adding a little air; we are hyper-oxygenating the plasma.

  • The Result: Dark, venous blood enters the machine and leaves as bright, vibrant, arterial-red blood.
  • The Benefit: This oxygen is delivered directly to your mitochondria (the power plants of your cells), drastically increasing ATP production and energy levels.
EBOO Therapy Machine, including BT100-3J peristaltic pump and Full Spectrum UV.
EBOO Therapy Machine – Photo by Revived Personalized Wellness

The “Versus” Battle: Why EBOO is the Gold Standard

There is a lot of confusion in the regenerative medicine world. Here is exactly how EBOO stacks up against older methods.

FeatureIV Ozone (MAH)10 Pass OzoneEBOO (The Gold Standard)
MethodGravity Drip / SyringeHyperbaric RecirculationContinuous Flow Filtration
Blood Treated~200 ml~200 ml (passed 10x)2,000+ ml (Full Volume)
FiltrationNoneNoneHigh-Efficiency Filter
Best ForMaintenance / Minor IssuesAcute InfectionsSystemic Detox / Chronic Illness

The Bottom Line:

  • EBOO vs. 10 Pass: 10 Pass is excellent for delivering a high dose of ozone, but it simply recirculates the same small amount of blood ten times. EBOO treats the entire blood supply, making it superior for systemic cleaning.
  • EBOO vs. IV Ozone: Standard IV ozone is beneficial but represents “old tech.” Comparing it to EBOO is like comparing a dial-up modem to fiber-optic internet.

For a more in-depth comparison, please read our article: EBOO vs. 10 Pass Ozone vs. Dialysis: Which Blood Therapy is Right for You?


The Conditions Driving the Trend

Why are patients flying across the country for EBOO? It targets the “stickiest,” most stubborn toxins that other therapies miss.

The “Spike Protein” & Long Covid

This is currently the number one driver of interest. Post-viral fatigue often lingers because the body struggles to clear circulating inflammatory proteins (including spike proteins) and micro-clots. EBOO’s unique filtration mechanism is theorized to physically capture and remove these heavy markers, often lifting the “brain fog” and fatigue associated with Long Covid after just a few sessions.

Mold Toxicity & Mycotoxins

Mold illness is notoriously difficult to treat because mycotoxins circulate in the blood, suppress the immune system, and re-circulate through the liver (enterohepatic recirculation). EBOO acts as a physical sieve, reducing the total toxic load in the blood so your body’s natural detox pathways (liver and kidneys) can finally catch up and function typically.

Lyme Disease & Biofilms

Chronic Lyme persists because bacteria (Borrelia) hide behind biofilms—a protective, slime-like shield that antibiotics often fail to penetrate. Ozone is a potent biofilm disruptor. By delivering high-dose ozone continuously, EBOO helps strip away these shields, exposing the pathogens to your immune system’s defenses.

Heavy Metal Detox

We live in a toxic world. From mercury in dental fillings to environmental lead and aluminum, these metals bind to our tissues and blood proteins. EBOO aids in the oxidation and mobilization of these metals, allowing them to be filtered out by the machine or excreted more efficiently by your kidneys post-treatment.


The Patient Journey: What to Expect

We remove the fear of the unknown by walking you through every step.

1. The Setup

You will sit in a comfortable treatment chair. A nurse will establish two IV lines—one in each arm (or sometimes a single specialized catheter). One line pulls the blood out; the other returns it.

2. The “Visual Proof.”

This is the moment patients remember most. You will watch your own blood flow into the machine.

  • Before: It often enters dark, almost maroon or black, signifying low oxygen and high toxin load.
  • After: It emerges from the filter bright, vibrant cherry red. This isn’t just aesthetic; it is proof of super-oxygenation happening in real-time.

3. The Debris

By the end of the session, the filter often captures a visible layer of foam or “sludge.” This visual evidence validates the therapy for many patients—you can literally see what was weighing your body down.

4. Duration & Sensation

A typical session lasts 45 to 60 minutes. The procedure is painless, though you may feel a slight cooling sensation as the blood returns to your body.

5. Recovery: The “EBOO Glow” vs. Herxheimer

Most patients feel an immediate clarity and energy boost, often called the “EBOO Glow.” However, because the detox is powerful, some patients with heavy viral loads may experience a “Herxheimer” reaction (mild fatigue, headache, or flu-like symptoms) as the body processes the die-off of pathogens. This is normal, a sign the therapy is working, and typically resolves within 24 hours.

How does EBOO Therapy work? Graphic diagram of the EBOO Treatment process.

Safety & Contraindications

We believe in transparency. EBOO is powerful, and it isn’t for everyone.

EBOO is generally considered safe when performed by certified professionals, and in full adherence to strict safety protocols. That said, as with many other medical procedures, several side effects may affect some individuals; it is not recommended for patients with:

  • G6PD Deficiency: This is a genetic enzyme deficiency that makes red blood cells vulnerable to oxidative stress. Some providers often require a blood test for this before treatment.
  • Uncontrolled Hyperthyroidism: Ozone increases metabolic rate, which can aggravate this condition.
  • Pregnancy: As a precaution, bio-oxidative therapies are generally avoided during pregnancy.
  • Recent Heart Attack or Severe Bleeding Disorders. The procedure requires the use of anticoagulants (Heparin) to ensure the consistency of the blood flow, which poses a risk for bleeding conditions. Additionally, the metabolic stimulation is contraindicated during the acute recovery phase of a heart attack.

Always consult with our qualified medical providers to determine if you are a candidate for this advanced therapy.


Bonus Video – EBOO Therapy in a Nutshell


EBOO Faqs

Does the procedure hurt?
Most patients report little to no discomfort. Aside from the initial pinch of the IV insertion (similar to a standard blood draw), the therapy itself is painless and often described as relaxing.
How long will I be in the clinic?
Plan for about 60 to 90 minutes total. The EBOO filtration process takes roughly 45 minutes, plus brief setup and post-treatment observation time.
How many sessions do I need?
For general wellness or a “reset,” 1-3 sessions are common. For chronic conditions like Lyme or mold toxicity, providers often recommend a protocol of weekly sessions for 4-6 weeks.
Is this covered by insurance?
EBOO is currently an elective therapy and not covered by standard insurance. However, many clinics accept HSA/FSA payments. Costs vary by location, typically ranging between $1,000 to $1,500 per session.
How do I find a safe clinic?
Safety is our priority. We have verified clinics across the US that meet strict equipment and safety standards. Search our directory here to find a provider near you.

You can find certified EBOO Therapy Providers and book your first session on our extensive Directory of EBOO Clinics

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